Document Details
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Document Type |
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Thesis |
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Document Title |
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Effect of Extra Intake of Some Oils and Fats on Some Behaviors, Morphological and Biochemical Characteristics on Mice Offspring تأثير الإفراط في تناول بعض أنواع الزيوت والدهون على بعض السلوكيات والصفات المورفولوجية والكيموحيوية في مواليد الفئران |
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Subject |
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biological sciences department |
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Document Language |
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Arabic |
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Abstract |
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This study aimed at identifying effects of fats added to diet (fish oil, sesame oil, ghee and sunflower oil) on sex ratio in progeny of mice, morphological traits, animal behavior (social, nonsocial and motivational) during growth before puberty and level of Cholesrtol (LDL, HDL), Thyroid gland hormones (TSH,T3,T4) and sex hormone (FSH) after maturity in both males and females. Twenty Five young female Swiss mice were feeded from day 21 till pubescence and mated with males feeded on controls and they give first progeny (F1). Males and females of F1 were mated, and their mothers were different and they were grown on the same type of food to get second filial generation (F2). It was found that in F2, mice feeded on ghee and sesame oils had more progeny than those feeded on other oils and number of males was higher than females. Mice feeded on sunflower had more female progeny in F1, followed by those feeded on ghee and sesame. Those feeded on fish oil had more females in both generations. Regarding morphological traits, group feeded on ghee had best traits and it was almost similar to control group followed by those feeded on sesame oil. While, those feeded on fish oil had the lowest traits, followed by sunflower oil. Weight of males was lower than controls in all groups. However mice feeded on ghee had higher weights than those feed on other fats and the lowest weight was recorded in females feeded on sunflower oil. Regarding behavior, males on ghee were the best group in social, learning and motivational behavior as well as memorization followed by sesame and fish oil feed groups. Blood analysis after maturity showed that concentration of fats increased levels of LDL and HDL more than controls, while their levels were decreased in those feeded on sunflower. Moreover, HDL level in males were higher in those feeded on ghee compared to those feeded on sunflower, while it was lower than normal in those feeded on fish oil.LDL did not affect female mice compared with males. Moreover, HDL was higher in females feeded on ghee compared to those feeded on sesame or sunflower oil, while those feeded on fish oil had their level constant. FSH was higher in mice feeded on sesame while in other groups remains constant. However, females feeded with high quantities of fats had significantly lower FSH concentrations than controls. Males on sesame oil had the highest levels of TSH in their blood, followed by those feeded on ghee in which T3 and T4 were higher than rest of groups. Group of mice feeded on sunflower oil showed an increase in TSH level more than all groups. T3 was very high in females feeded on ghee followed by those feed on sesame and fish oils and the lowest level was in mice feed on fish oil. Regarding TSH, group of mice feeded on Sunflower had higher level than groups feeded on ghee, fish and sesame oil. |
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Supervisor |
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dr.Khaled B Kamal |
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Thesis Type |
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Master Thesis |
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Publishing Year |
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1433 AH
2012 AD |
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Added Date |
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Tuesday, June 5, 2012 |
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Researchers
| وجدان مصطفى حناوي | Henawi, Wejdan Mostafa | Researcher | Master | |
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