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Document Type |
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Thesis |
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Document Title |
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Prevalence Study of Hepatitis A Virus (HAV) in Jeddah Population دراسة انتشار عدوى فيروس التهاب الكبد الوبائي (أ) بين سكان جدة |
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Subject |
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biological sciences department |
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Document Language |
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Arabic |
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Abstract |
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Hepatitis A is an acute disease in the liver, which results from infection with hepatitisA. The mortality rate tends to increase with age, in particular, when greater than 40 years of age. HAV infection is one of the most important public health problems all over the world, especially in areas with high prevalence rate of HAV. Prevalence of HAV infection shows great differences not only between different countries but also between different regions in the same country. It is inversely related to the level of socioeconomic status, sanitation and personal hygiene. Saudi Arabia is a part of our world. Jeddah is a big city that is growing in population and facing an increase in restaurants. Unfortunately,lots of families buy food from restaurants and eat food that is not prepared at home. These factors participated
in spreading Hepatitis A virus. The objective of this study is to investigate on the prevalence of Hepatitis A virus (HAV) in Jeddah population, Saudi Arabia. Also to find out the relationship HAV infection of our results with age, gender and ethnicity. Serum samples were collected from studied population between 2 and 35 or more years of age and stratified into the following age groups: 2 to 5, 6 to 9, 10 to14, 15 to19, 20 to 24, 25 to 29, 30 to 34 and more than 35 year, Serum samples were not available for less than 2 year of age. Serum samples also were stratified according to nationality into Saudi and non Saudi. Serum samples were stratified into male and female. Samples size were calculated to achieve a 95% confidence interval (CI) of approximately ±5% for each age group. The determination of antibody(IgG) was carried out by ELISA-test. For all age groups, there was no significant difference between genders regarding anti-HAV seropositivity. The prevalence of IgG antibodies to HAV was 33.1% overall, 33.6% among males and 32.5% among females with no statistically significant difference (P>0.05). However, it increased significantly with the age. The IgG antibodies to HAV were found in 20.3 % of Saudi population, and 49% of non Saudi population (p<0.05). The prevalence of HAV among adult population (39.3%) was higher than among children population (22.4%). The chi-square test showed significant differences in the prevalence of HAV between adult and children populations (p<0.05). |
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Supervisor |
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Dr.Mohamed Morsi. M. Ahmed |
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Thesis Type |
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Master Thesis |
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Publishing Year |
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1433 AH
2012 AD |
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Added Date |
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Sunday, July 29, 2012 |
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Researchers
| ماهر حسن با بعير | Babaeer, Maher Hassan | Researcher | Master | |
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