Deanship of Graduate Studies | Researches | Histological and Histochemical Studies on the Effect of Rhazya stricta Extract on the Mice and the possible Protective Role Against Leurius quinquestriatus Scorpion Venom

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Document Details

Document Type	:	Thesis
Document Title	:	Histological and Histochemical Studies on the Effect of Rhazya stricta Extract on the Mice and the possible Protective Role Against Leurius quinquestriatus Scorpion Venom دراسات نسيجية وكيمياء نسيجية على تأثير مستخلص نبات الحرمل على الفئران و الدور الوقائي المحتمل ضد تأثير سم العقرب (ليورس كوانكستراتس)
Subject	:	biological sciences department
Document Language	:	Arabic
Abstract	:	The Saudi ecosystem possesses a plenty of medicinal plant species, which are used by public for treating different types of diseases and health problems. It has been noticed that the use of these plants depends on folkloric descriptions with any dose and for different durations, which are usually based on no scientific principles or medical prescription. These uses can lead to the occurrence of some side effects or health injuries for the human.Therefore, the present study was planned to examine the effect of Rhazya stricta extract, which is widely used in Saudi, on the tissues and cells of the experimental animals after different durations of extract administration. The study examine the possibility of using the plant extract in reducing the toxic effect of the venom of one of the common scorpions in Saudi Arabia, Leurius quinquestriatus.The study included four groups: (I) A control group (orally treated daily with distilled water for 45 days, then intramuscularly injected with saline solution and sacrificed after 6 hrs from injection). (II) Plant treated group (orally treated daily with the Rhazya stricta plant extract for 15, 30 and 45 days). (III) Venom group (intramuscularly injected with LD50 of the scorpion venom). (IV) Plant-venom treated group (orally treated as in group II followed by intramuscular injection with the venom as in group III). By the end of each experiment, mice were sacrificed and samples from their tissues were removed and prepared for histological, cytological and Immunohistochemical studies.
Supervisor	:	Prof .Osama A. Abu-Zinadah
Thesis Type	:	Doctorate Thesis
Publishing Year	:	1434 AH 2013 AD
Co-Supervisor	:	Prof. Tarek R. Rahmy
Added Date	:	Wednesday, May 1, 2013

Researchers

Researcher Name (Arabic)	Researcher Name (English)	Researcher Type	Dr Grade	Email
حسن عتيق الحربي	Al -Harbi, Hassan Ateeq	Researcher	Doctorate

Files

File Name	Type	Description
35537.pdf	pdf

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