Document Details

Document Type : Thesis 
Document Title :
Effect of Energy Drinks on Rats Ovary
تأثير مشروبات الطاقة على المبيض في الجرذان
 
Subject : biological sciences department 
Document Language : Arabic 
Abstract : This study examined the effects of energy drinks (Code Red, Power Horse, Red Bull) on the ovary of Wister Albino Rats, and progesterone and estrogen hormones, as well as some biomarkers in the blood include (red blood cells, white blood cells, platelets, cholesterol , triglycerides and glucose), for periods of 45 days and 90 days of treatment. Body weight results of animals of 45 days of treatment showed a significant decrease (p = 0.003) in the body weight of C Group, compared with the control group. There was no significant differences in ovary weight after 45 days of treatment in all experimental groups. After 90 days found a significant decrease (p = 0.001) in the body weight of B, C and D groups, compared with the control group. Ovarian weights also showed a significant decrease (p = 0.001) in the ovary weights of D group, compared with the control group. The results of this study showed a significant decrease (p = 0.001) in the number of white blood cells of C and D groups, compared with the control group after 45 days of treatment. While after 90 days of treatment a significant decrease (p = 0.01) in the number of white blood cells of D group was noticed, compared with the control group. As for the red blood cells did not have any significant differences in 45 and 90 days of treatment. This study also showed a significant decrease (p = 0.007) in the number of platelets of B and C groups, compared with the control group after 45 days of treatment, while there was a significant decrease (p = 0.02) in the number of platelets of C group compared with the control group after 90 days of treatment. And showed a significant increase (p = 0.03) in the level of glucose of B group compared with C and D groups after 45 days of treatment, while after 90 days a significant increase (p = 0.001) in the level of glucose of D group compared with the control group and B and C groups. As for cholesterol high density HDL and low density LDL after 45 days of treatment a significant decrease (p = 0.007) in the level of HDL of D group compared with the control group and a significant increase (p = 0.001) in the level of (LDL) of D group compared with the control group. While there was no significant differences between all groups after 90 days of treatment. The results of this study also showed a significant increase (p = 0.009) in the level of triglycerides of D group compared with the control group, and there was no significant differences between groups after 90 days of treatment. Hormones values showed differences between groups. There was a significant increase (p = 0.001) in the level of progesterone of D group compared with the control group and B and C group, and a significant increase (p = 0.001) in the level of estradiol of B and C groups, compared with the control group after 45 days of treatment. While after 90 days of treatment there was a significant increase (p = 0.001) in the level of progesterone of B, C and D groups, compared with the control group, and a significant increase (p = 0.001) in the level of estradiol of D group compared with the control group and C group. Light microscopic examination of the tissues in the ovarian sections of B, C and D groups, showed congestion of the ovarian blood vessels and degeneration of the graffian follicles and complete absence of ova from ovarian follicles, in other cases. This may be attributed to the effect of caffeine present in energy drinks component, Our findings revealed that some follicles were destructed and replaced by fibrous connective tissue with presence of follicular atrasia in the ovary and infiltration of white blood cells in the ovarian tissue with perivascular fibrosis. 
Supervisor : Dr. Mohammed Ibrahim Mujallid 
Thesis Type : Master Thesis 
Publishing Year : 1434 AH
2013 AD
 
Added Date : Sunday, September 1, 2013 

Researchers

Researcher Name (Arabic)Researcher Name (English)Researcher TypeDr GradeEmail
غالية حسين المالكيal-Maleki, Ghaliah HusseinResearcherMaster 

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