Document Details

Document Type : Thesis 
Document Title :
Predictive Value of Centor Criteria versus Microbiological Investigation of Sore Throat in Children
الدقة التشخيصية لعلامات التنبؤ السريرية لالتهاب الحلق بالمكورات العقدية لدى الاطفال مقارنة بالتشخيص المخبري الميكروبي
 
Subject : Faculty of medicine 
Document Language : Arabic 
Abstract : Background: Sore throat is a common problem during childhood and is usually the result of bacterial or viral infection. Group A Streptococcus (GAS) is the most common bacterial cause; up to thirty percent (30%) of children with a sore throat. There are many viruses that cause sore throat of an upper respiratory infection named “common cold”. Other viruses include Influenza, Enterovirus, Adenovirus and Epstein-Barr virus (the cause of mononucleosis). Objectives: Estimating the clinical decision rules (CDRs) predicting biostatistics value of Centor criteria/Rapid Antigen Detection Test (RADT) to find the positive and negative predictive value, sensitivity, specificity versus gold standard method. Method: Diagnostic prospective cohort study involving fifty patients (50) with 15 years or less conducted at primary health care clinic at National Guard Specialized Polyclinics in Jeddah, Two throat swabs samples were collected from patient: one for laboratory culture of GAS, the other for RADT. Data collection were being filled according to physician (Appendix D). Results: The present study finds a significant relation between total Centor criteria score and indication of antibiotic at p-value < 0.000, sensitivity (50%), specificity (100%), the positive predictive value and negative predictive value (100%) & (88.88%) respectively, significant relation between culture result and RADT bedside patients at p-value < 0.001, sensitivity (90%), specificity (100%), the positive predictive value and negative predictive value (100%) & (97.56%) respectively. Conclusions: RADT tend to increase the sensitivity of diagnosis bacterial pharyngitis in comparing to the presence of signs and symptoms in Centor criteria score. Key word: GAS (Group A Streptococcus), RADT (Rapid Antigen Detection Test), CDRs (Clinical Decision Rules). 
Supervisor : Prof. Asif M. Jiman-Fatani 
Thesis Type : Master Thesis 
Publishing Year : 1441 AH
2020 AD 
Co-Supervisor : Dr. Mohammed Saad Almuhayawi 
Added Date : Monday, June 8, 2020 

Researchers

Researcher Name (Arabic)Researcher Name (English)Researcher TypeDr GradeEmail
محمد شكيب شولقShakeeb, Mohammed ShowlagResearcherMaster 

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